Package Centre
Mixing Package
Ensure a robust scale-up by computationally obtaining hard-to-measure mixing times of your system following the Bourne protocol at lab scale.
- Crystallizations
- Mixing critical systems
- Avoid uncontrolled nucleation
- Increase reaction efficiency
- Avoid shortcuts
- Obtain robust process conditions
CFD-based Reduced Order Model
Obtain a reduced order model (ROM) of your system and explore unseen system states in real-time for optimization or predictive maintenance.
- Industry and system independent
- Enable 3D resolved fluid dynamics for predictive maintenance
- Enable optimization with 3D resolved fluid dynamics
- Accelerate project progress through quick decisions
- Enable results live discussion with colleagues
- Retrain ROM with updated data at any time
Reactor CFD Data Base
Combine with package “Reactor Mapping and Digitalization” and complement it with CFD simulations for all your reactors.
- Full CFD results at different operating conditions
- Statistics of process relevant scale-up quantities
- Full distributions of all fluid dynamic quantities
- More accurate compared to correlations
- Flexible for interfacing with internal tools
- De-risking of scale-up and process transfers
Reactor Mapping and Digitalization
Map all your lab, pilot and commercial reactors and make process relevant equipment information easily accessible.
- Mapping all reactors
- 3D Geometrical build-up and 3D scanning of lab impellers
- Web application for data access with reactor viewer
- Access data from anywhere at anytime
- Ensure data integrity for standardised sharing
- Unlock our Fast Lane Support
Vial Filling Line Optimization
Apply optimal stirring by gradually adjusting the stirring speed during vial filling, ensuring homogeneity while avoiding foaming.
- Stirred vessel vial filling
- First-time-right scale-up
- Higher yields
- Consistent API concentration in vials
- Supports GMP approval
- Large ROI
Crystallization Scale-up and CDMO Transfer
Select correct reactor configurations and operating conditions to ensure consistent product quality and compliance with specifications.
- Crystallizations
- Mixing crtitical systems
- API solids suspensions
- First-time-right scale-up
- No time delays through repetition
- Large ROI
Foaming Control in Stirred Reactors
Select the correct agitation speed to avoid foaming and realise larger batch sizes through higher fill levels.
- Gas-liquid mass transfer systems
- API solids suspensions
- Vial filling
- Avoid antifoams and product re-registration
- Conservation of API solids concentration
- Large ROI
Particle Suspensions and Dispersions
Select the optimal stirring speed to ensure homogeneity in dispersions and for suspending particles just as required by the process.
- Filter-feeding bottom discharge tank
- Crystallizations
- Processes critical to API concentration
- Eco-friendly process operation
- Consistent product quality
- Large ROI